Synthesis, Characterization and Bioactivities of Some Novel Oxovanadium(IV) Glycinato Complexes

  • Mohammad K. Islam Department of Chemistry, Faculty of Science, Mawlana Bhashani Science and Technology University, Santosh, Tangail-1902, Bangladesh
  • Md. Nuruzzaman Department of Chemistry, Faculty of Science, Mawlana Bhashani Science and Technology University, Santosh, Tangail-1902, Bangladesh
  • Rashedul I. Ripon Department of Chemistry, Faculty of Science, Mawlana Bhashani Science and Technology University, Santosh, Tangail-1902, Bangladesh
  • Md. Shalauddin Department of Chemistry, Faculty of Science, Mawlana Bhashani Science and Technology University, Santosh, Tangail-1902, Bangladesh
  • Foni B. Biswas Department of Chemistry, Faculty of Science, University of Chittagong, Chittagong-4331, Bangladesh
  • Mamun M. Hossain Department of Chemistry, Faculty of Mathematical and Physical Sciences, Jahangirnagar University, Savar, Dhaka-1342, Bangladesh
  • Mohammad R. Islam Department of Chemistry, Faculty of Mathematical and Physical Sciences, Jahangirnagar University, Savar, Dhaka-1342, Bangladesh
  • Sumaiya Khan Department of Chemistry, Faculty of Mathematical and Physical Sciences, Jahangirnagar University, Savar, Dhaka-1342, Bangladesh

Abstract

The novel oxovanadium(IV) complexes, [VIVO(GlyH)(Gly)]+ClO4 - .H2O (1), [VIVO(GlyH)(Gly)]+NO3 - .H2O (2), [VIVO(GlyH)(Gly)]+CH3COO- .H2O (3) were synthesized and characterized by FT-IR, UV-Vis and 1H NMR spectroscopic measurements. The cumulative spectroscopic assessment envisaged that, the complexes adopt a square pyramidal structure, in which the two glycine ligands coordinate to vanadium(IV) center in bidentate fashions conforming a homoleptic structure. The amino nitrogen and a carboxylato oxygen atom coordinate the vanadium(IV) center from both sides making a five members chelate by each side. All the complexes are stable in amorphous state and in aerobic and anaerobic solution. Significantly, all the complexes have the antifungal activities against Aspergillus niger and Penicillium notatum but ineffective against Candida tropicalis. No antibacterial activity was observed for the complexes against tested bacteria and unfortunately, they were found cytotoxic against brine shrimp bioassay.

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Published
2018-07-31
How to Cite
Islam, M. K., Nuruzzaman, M., Ripon, R. I., Shalauddin, M., Biswas, F. B., Hossain, M. M., Islam, M. R., & Khan, S. (2018). Synthesis, Characterization and Bioactivities of Some Novel Oxovanadium(IV) Glycinato Complexes. European Scientific Journal, ESJ, 14(21), 410. https://doi.org/10.19044/esj.2018.v14n21p410