T-cell/Histiocyte-rich Large B-cell Lymphoma in an Adolescent from Abidjan-Ivory Coast: Case Report
Abstract
T-cell/Histiocyte-rich large B-cell lymphoma (THRLBCL) is a rare pathology, uncommon in the children population, and the few cases reported had a wide range of clinical presentations, including advanced stage, extranodal involvement, and bad prognosis. The authors report a case of a 16-year-old male patient with no medical history, who presented a single left axillary adenopathy. T-cell/Histiocyte-rich large B-cell lymphoma was diagnosed by immunohistochemistry and was classified good prognosis. RCHOP-based chemotherapy was performed with good progress. The authors hope to contribute to the literature on THRLBCL and draw the attention of practitioners to its occurrence in the pediatric population.
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2. Bouabdallah, R., Mounier, N., Guettier, C., Molina, T., Ribrag, V., Thieblemont, C., Sonet, A., Delmer, A., Belhadj, K., & Gaulard, P. (2003). T-cell/histiocyte-rich large B-cell lymphomas and classical diffuse large B-cell lymphomas have similar outcome after chemotherapy: A matched-control analysis. Journal of clinical oncology, 21(7), 1271 1277.
3. Campo, E., Jaffe, E. S., Cook, J. R., Quintanilla-Martinez, L., Swerdlow, S. H., Anderson, K. C., Brousset, P., Cerroni, L., de Leval, L., Dirnhofer, S., Dogan, A., Feldman, A. L., Fend, F., Friedberg, J. W., Gaulard, P., Ghia, P., Horwitz, S. M., King, R. L., Salles, G., … Zelenetz, A. D. (2022). The International Consensus Classification of Mature Lymphoid Neoplasms: A report from the Clinical Advisory Committee. Blood, 140(11), 1229‑1253. https://doi.org/10.1182/blood.2022015851
4. Chan, A., & Chan, J. (2017). Diffuse large B-cell lymphoma. In Hematopathology (2nd éd., p. 433 437). Phiadelphia, PA: Elsevier.
5. Cornillie, J., Tousseyn, T., & Verhoef, G. (2012). T-cell/histiocyte-rich large B-cell lymphoma: Review on pathologic diagnosis, current therapeutic options, and new targets for therapy. Belg J Hematol, 3(4), 128 133.
6. El Weshi, A., Akhtar, S., Mourad, W. A., Ajarim, D., Abdelsalm, M., Khafaga, Y., Bazarbashi, S., & Maghfoor, I. (2007). T-cell/histiocyte-rich B-cell lymphoma: Clinical presentation, management, and prognostic factors: report on 61 patients and review of literature. Leukemia & lymphoma, 48(9), 1764 1773.
7. Gheorghe, G., Rangarajan, H. G., Camitta, B., Segura, A., Kroft, S., & Southern, J. F. (2015). T-cell/histiocyte-rich large B-cell lymphoma in pediatric patients: An under-recognized entity? Annals of Clinical & Laboratory Science, 45(1), 73 78.
8. Ioachim, H. L., & Ratech, H. (2002). Nomenclature and classification of lymphomas. Ioachim Lymphnode Pathology. 3rd ed. Philadelphia: Lippincott Williams and Wilkins, 315 324.
9. Pittaluga, S., & Jaffe, E. S. (2010). T-cell/histiocyte-rich large B-cell lymphoma. Haematologica.
10. Prasaad, P. R., & Badhe, B. A. (2018). Non-Hodgkin lymphomas–T cell type: Histomorphology and immunohistochemistry. Indian Journal of Pathology and Oncology, 5(4), 636 641.
11. Swerdlow, S. H. (2008). WHO classification of tumors of haematopoietic and lymphoid tissues. WHO classification of tumors, 22008, 439.
12. Wei, C., Wei, C., Alhalabi, O., & Chen, L. (2018). T-cell/histiocyte-rich large B-cell lymphoma in a child: A case report and review of literature. World Journal of clinical cases, 6(6), 121.
Copyright (c) 2023 Ismael Kamara, Kodzovi Mawulé Corcellar Womey, Dohoma A. Silué, Réné-Paule Botti, Ruth Djeke, Boidy Kouakou, Gustave Koffi
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