SYNTHESIS AND CRYSTAL STRUCTURE ANALYSIS OF 3 - (4 - METHOXYBENZYL) - 2, 3 – DIHYDRO - 4H – CHROMAN – 4 - ONE

  • Lalitha Simon Department of Chemistry, Manipal Institute of Technology, Manipal University, Manipal
  • S. Shalini Chemistry Research Centre, SSMRV Degree College, Jayanagar, Bangalore
  • C. R. Girija Chemistry Research Centre, SSMRV Degree College, Jayanagar, Bangalore
  • K.K. Srinivasan Department of Pharmaceutical Chemistry, Manipal College of Pharmaceutical Sciences, Manipal
  • T.V. Venkatesha Department of Chemistry, Jnana Sahyadri, Kuvempu University, Shankargatta

Abstract

3-(4-methoxybenzyl)-2,3-dihydro-4H-chroman-4-one(C17H16 O3) was synthesized by refluxing 2'-Hydroxydihydrochalcone dissolved in ethanol with paraformaldehyde and 50% aqueous diethylamine. The compound is characterized by IR,1HNMR, MS and X-ray diffraction studies. The X-ray structure analysis indicates that the crystal suffers from the positional disorder over two positions, atomC1 and C9 with required site occupancies of 0.590 and 0.410 leading to a conformational difference between the major and minor components. After applying similarity restraints, the final reliability index is 0.0275 for 2209 unique reflections .The crystal packing is stabilized by inter molecular C-H…O, C-H…π and π …π interactions.

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Published
2013-08-31
How to Cite
Simon, L., Shalini, S., Girija, C. R., Srinivasan, K., & Venkatesha, T. (2013). SYNTHESIS AND CRYSTAL STRUCTURE ANALYSIS OF 3 - (4 - METHOXYBENZYL) - 2, 3 – DIHYDRO - 4H – CHROMAN – 4 - ONE. European Scientific Journal, ESJ, 9(24). https://doi.org/10.19044/esj.2013.v9n24p%p