NATURAL POLYMER OF TAMARIND SEED: A PROSPECTIVE CARRIER FOR OCULAR DRUG DELIVERY

  • Rashmirekha Sahoo Program Head FIS, Melaka Manipal Medical College, Malaysia
  • Soumendra Sahoo Head, Ophthalmology, Melaka Manipal Medical College, Malaysia

Abstract

Natural polysaccharide-based biomaterials are currently being explored as novel drug delivery devices. Important properties of the polysaccharides include controlled biological activity and biodegradability. The tamarind seed is a by-product of the tamarind industry. The decorticated flour, known as tamarind kernel powder has been tried for various biomedical applications such as drug delivery carriers. The xyloglucan component of it, a hemicellulose, was found to be a biocompatible, non-toxic and cheap agro-based material that could be used safely for controlled drug delivery systems. Studies with tamarind-seed polysaccharide nanocomposites have been conducted, where tamarind and polyvinyl alcohol were blended with Cloisite 30B solution in different ratios showing a sustained delivery of drugs. We certainly foresee the prospect of bioadhesive carriers, such as muco-adhesive polymers of tamarind-seed polysaccharides an effective solution of achieving bioavailability of various ocular drugs when used as topical preparations

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Published
2015-09-29
How to Cite
Sahoo, R., & Sahoo, S. (2015). NATURAL POLYMER OF TAMARIND SEED: A PROSPECTIVE CARRIER FOR OCULAR DRUG DELIVERY. European Scientific Journal, ESJ, 11(27). Retrieved from https://eujournal.org/index.php/esj/article/view/6275